Cardiovascular Drugs 0.0 / 5 ? OtherParamedic sciencePharmocologyUniversityNone Created by: LouisaCreated on: 31-10-20 15:38 what does hypertension do to the body damanges blood vessels, accelerates atherosclerosis and causes elft ventricular hypertrophy 1 of 33 What 4 categories of drugs an reduce blood pressure Diuretics, sympatholytics, angiotensin inhibitors, vasodialators 2 of 33 diuretics do what increases renal sodium excretion 3 of 33 4 types of diuretics Thiazide diurectics - treat HTN Loop diuretics - treat when above doesn't work potassium - sparing diuretis osmotic diuretics 4 of 33 sympatholytics are what type of drug adrenoreceptor antagonist 5 of 33 types of sympatholytics selective a (alpha) blockers b (beta) blockers 6 of 33 beta blockers reduce Bp by ... reducing cardiac output bt reducing heart rate ad contractibility. 7 of 33 Angiotensin inhibitors do what inhibit the renin-angiotensin system somehow 8 of 33 ACE inhibitors block the production of what what binds to the active site the enzyme ACE that converts angiotensis 1 into angiotensis 2, causing vasodilation zinc atom in the active site 9 of 33 Angiotensin receptor blocks (ARBs) block what causing what to occur overall... block angiotensin receptors reduces vasoconstriction, aldosterone secretion and Na reabsorption in proximal tubule reducing cardiac output 10 of 33 what is congestive heart failure weakening of the ventricles = impaired ability for the heart to pump 11 of 33 what is furosemide what does it do loop diuretic inhibits Na+, k+ and 2cl- in loop of henle 12 of 33 what drug types are vasodialators ACE inhibitors and ARBs and GTN 13 of 33 What is coronary heart disease includes what all are caused by angina pectoris, unstable angina, MI coronary artery ischaemia 14 of 33 what causes coronary artery ischemia thrombi, coronary vasospasm and atherosclerosis 15 of 33 what is coronary heart disease treated by organic nitrates and nitrites calcium channel blockers b-adrenoreceptor antagonists preventative agent 16 of 33 drugs aim to balance the oxygen supply and demand 17 of 33 calcium channel blockers included which drugs where are Ca channels located amlodipine, nifedipine, diltiazem, verapamil plasma membrane of cardiac and smooth muscle tissue 18 of 33 an influx of Ca+ causes membrane depolarisation and initiates or strengths muscle contraction 19 of 33 calcium channel blockers bind to causes a stopping a blocking the ca+ influx supresses the calcium channels conformational change influx of ca+ through the channels cardiac activity and relaxes the smooth muscle 20 of 33 B-adrenoreceptor drugs atenolol, bisoprolol and propranolol 21 of 33 what do B-adrenoreceptor drugs prevent tachycardia, improve myocardial blood supply 22 of 33 what drug is an antiplalet Aspirin 23 of 33 what does an antiplatlet drug do inhibit platlet aggregation 24 of 33 aspirin has what properties antipyretic, anti-inflammatory and analgesic effect 25 of 33 other antiplatlet drug we carry on the ambo clopidogrel 26 of 33 what does clopidogrel block ADP (which promotes platelet aggression) 27 of 33 oral anticoagulants warfarin, rivaroxaban and dabigatran 28 of 33 warfarin works by side effect inhibit vitamin K - a dependent clotting factor bleeding 29 of 33 new oral anticoagulants apixaban, rivaroxaban and new oral anticoagulants 30 of 33 advantagesover warfarin fewer drug food interactions lower risk of haemorrhagic stroke effect stops sooner that warfarin if stopped however no antidote 31 of 33 Thrombolytic drugs retaplase, tenecteplase and streptokinase 32 of 33 thrombolytic drugs activate dissolve side effect activate plasminogen and enhance fibrinolysis thrombi and fibrin at sites of vascular injury Haemorrhage is a side effect 33 of 33
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