Cancer Biology Topic 3

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chemicals that damage DNA due to physical factors or chemicals
carcinogens
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codes for proteins that stimulate the transition from one cell cycle to the next
oncogene
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tumour suppressor protein which stops the cell cycle by inhibiting enzymes at G1/S transition, preventing the cell from copying its DNA
p53
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produces suppressor gene which stops the cell cycle
tumour suppressor genes
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mutations on this gene makes a person more susceptible to breast cancer
BRCA1
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where the carcinogens in smoking are mostly
tar
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damages DNA in skin cells
UV light
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destroy radicals
antioxidants
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contribute to aging and cancer by damaging DNA
radicals
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can cause cancers but can be vaccinated against
virus infections
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can cause liver cancer
hepatitis
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can cause cervical cancer
papilloma virus
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what can be picked up by the virus from the host
oncogenes
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normal gene of this produces a protein that repairs DNA
BRCA1
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more likely to occur in tissues with a high rate of mitosis
cancer
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Other cards in this set

Card 2

Front

codes for proteins that stimulate the transition from one cell cycle to the next

Back

oncogene

Card 3

Front

tumour suppressor protein which stops the cell cycle by inhibiting enzymes at G1/S transition, preventing the cell from copying its DNA

Back

Preview of the front of card 3

Card 4

Front

produces suppressor gene which stops the cell cycle

Back

Preview of the front of card 4

Card 5

Front

mutations on this gene makes a person more susceptible to breast cancer

Back

Preview of the front of card 5
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