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6. What is the name of the process by which sugar molecules are added to a polypeptide?

  • Acetylation
  • Lipidation
  • Sumoylation
  • Glycosylation
  • Phosphorylation

7. An electrophoretic mobility shift assay (EMSA)...?

  • Directly shows binding of nuclear proteins to a specific part of the promoter
  • Tests for transcriptional activity
  • Inhibits transcription
  • Tests for translational activity
  • Inhibits translation

8. The histone octamer core comprises...?

  • 2xH2A/H2B + 2xH3/H4
  • 4xH2A/H2B
  • 2xH1/H2A + 2xH1/H2B
  • 4xH2A/H3
  • 2xH2A/H3 + 2xH2B/H4

9. In which direction does DNA polymerase move?

  • 5' to 3'
  • right to left
  • upwards
  • 3' to 5'
  • left to right

10. Which AA causes a 'kink' in the polypeptide chain?

  • Phenylalanine
  • Proline
  • Alanine
  • Glutamine
  • Glycine

11. How is diversity generates during meiosis?

  • Synthesis and crossing over
  • Synapsis and crossing wires
  • Synapsis and crossing over
  • Synthesis and crossing under

12. Centromeres.....?

  • A and C
  • B) protect the ends of chromosomes
  • A and B
  • A) consist of satellite DNA
  • C) anchor chromosomes to spindles

13. What is the name of the tandem repeat of type CA(n) or CACACACACA?

  • Microsatellites
  • Micro and Mini
  • Minisatellites
  • Satellites

14. Which type of DNA binding domain is found in nuclear receptors?

  • Basic helix loop helox
  • Helix turn helix
  • Zinc finger
  • Leucine zipper

15. Which of the following is true about cancer?

  • SNPs may increase the risk
  • all the things
  • cancer may involve DNA repair defects
  • there are monogenic forms
  • cancer is a complex disease

16. What is the start codon for translation in mRNA?

  • AUG
  • GAG
  • AAG
  • GGA
  • UGA

17. A heterodimeric nuclear receptors...?

  • Translocates into the nucleus on ligand binding
  • Binds to RNA polymerase
  • Doesnt require ligand binding for activity
  • Is exclusively in the nucleus
  • Remains in the cytoplasm

18. Single nucleotide polymorphisms are...?

  • common
  • always advantageous
  • rare
  • always deleterious
  • always neutral

19. What structure is found on the 5' end of a mature mRNA?

  • CAP
  • CAR
  • CAT
  • HAT
  • DOG

20. What is the process in eukaryotes whereby ribosomes find the start site of translation?

  • Writing
  • Reading
  • Scanning
  • Gliding
  • Sliding