BMS1031 human genetics

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1. How is diversity generates during meiosis?

  • Synthesis and crossing under
  • Synapsis and crossing over
  • Synapsis and crossing wires
  • Synthesis and crossing over
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2. Which type of histone tail modification always leads to activation of gene expression?

  • Glycosylation
  • Methylation
  • Dephosphorylation
  • Acetylation
  • Phosphorylation

3. A reporter gene assay...?

  • Directly shows binding of nuclear proteins to a specific part of the promoter
  • Tests for transcriptional activity
  • Test for translational activity
  • Inhibits translation
  • Inhibits transcription

4. Which type of repeats are polymorphic and used in DNA fingerprinting?

  • Micro and Mini
  • Satellites
  • Microsatellite
  • Minisatellite

5. A base change that leads to insertion of a stop codon may cause mRNA to be degraded by...?

  • All the things
  • Nonsense-mediated decay
  • RNA polymerase
  • Sense-mediated decay
  • Proteolytic cleavage

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