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6. 283 Rhesus monkeys. Kinship known. Glucose matabolite and threat. Anxious temperament correlated with HIP and AMG. Only HIP heritable, Anterior HIP.

  • Oler et al (2010)
  • Davidson et al (2009)

7. SP scores positively correlate with right hippocampal volume (0.33) and well as absolute volume (0.38).

  • Lever et al (2014)
  • Coan and Allen (2004)

8. Individual differences in anxiety represent personality traits.

  • Cattle (1996)
  • Brett et al (2001)

9. SPSRQ validated, scores could predict GAD dignosis.

  • Maack et al (2012)
  • Torrubia et al (2001)

10. Found BIS scores were associated with increased HIP and AMG grey matter. 63 males.

  • Avila et al (2006)
  • Lever et al (2014)

11. Anxiety research often considered the hippocampus and amygdala for controlling behaviour inhibition, but also that evidence is indefinite..

  • Graham et al (2011)
  • Fuentes et al (2012)

12. 114 males. BIS associated with reduced precunenus and OFC but not AMY and HIP. Emotion and self-consciousness.

  • Fuentes et al (2012)
  • Brett et al (2001)

13. State trait anxiety questionnaire.

  • Speilberger (2010)
  • Oler at al (2010)

14. Rats bread to be more anxious or put in calming environment. Both had an effect on HIP and AMG.

  • Torrubia et al (2017)
  • Wright et al (2006)

15. Bran activity. Connectivity between AMG and HIP correlated with sensitivity to punishment. (0.66) Explains 1/3 of varience in SP scores. Co-modulation.

  • Hahn et al (2010)
  • Meany (2001)

16. Anterior cingulate cortex and 2 cell populations encoding for positive and negative attitudes towards a situation. Pregenual zone in ventral bank all negative.

  • Amemori and Graybeil (2012)
  • Avila et al (2006)

17. Anxiety is an emotional state characterised by worry, rumination and nervousness.

  • Spielberg (2010)
  • Cherbin et al (2008)

18. Depression associated with smaller hippocampus.

  • E.g. Sheline et al (1996)
  • Amemori and Graybiel (2012)

19. Anxiety on a continuous spectrum, the high end of which can result in clinical diagnosis.

  • Gray and McNaughton (2000) (1)
  • Davidson et al (2009)

20. Variations in maternal care might alter expression of genes which control for hippocampal synaptic development.

  • Meany et al (2001)
  • Graham et al (2011)