Biology Unit 6 - Non Specific Response

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3 components?
Inflammation, Interferons & Phagocytosis
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What is the site where the pathogen enters the body called?
The site of infection
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What do immune system cells do?
Recognise the foreign antigens and therefore release molecules that trigger inflammation
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What do these molecules do? (2)
1) Trigger vasodilation 2) Increase permeability of blood vessels
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Why do the molecules cause vasodilation (widening)?
To bring more immune cells to destroy pathogen
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What does increased permeability allow?
The immune cells to move out of blood vessel and into infected tissue - to destroy the pathogens
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When are interferons produced?
When cella are infected with viruses
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They are a type of what?
Virus
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What do interferons do?
Stop viruses spreading to uninfected cells
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How do they do this?
1) Prevent viral replication (inhibit production of viral proteins) 2) Active specific IR cells to kill infected cells 3) Activate other mechanisms of non specific IR
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A phagocyte is a type of
WBC
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What is phagocytosis?
Engulfment of a pathogen
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How do they engulf pathogens?
Their cytoplasm moves around the pathogen and takes it in
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What is the pathogen contained in inside the phagocyte?
Phagocytic vacuole
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How is the pathogen destroyed?
Lysosomes (containing lysozymes) fuse with vacuole and break down pathogen
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What does the phagocyte then do?
Presents the antigens on its surface so activate other immune cells (APC)
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Other cards in this set

Card 2

Front

What is the site where the pathogen enters the body called?

Back

The site of infection

Card 3

Front

What do immune system cells do?

Back

Preview of the front of card 3

Card 4

Front

What do these molecules do? (2)

Back

Preview of the front of card 4

Card 5

Front

Why do the molecules cause vasodilation (widening)?

Back

Preview of the front of card 5
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