Conventional Antipsychotics - Dopamine Antagonists in that they bind to the dopamine receptors but do not stimulate then thus blocking their action
By reducin stimulation of the dopamine system in the brain, antipsychotic drugs can eliminate the hallucinations and delusions experienced by people with schizophrenia
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Atypical - Newer and less widely used - Have fewer side effects and act in different ways to antipsychotic drugs
Atypicals such as Clozapine, work differently in that they attach to specific DZ dopamine receptors. Good for positive systems, however comparative affects on negative are marginal (Leucht et al)
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Side effects of antipsychotics
Drowsiness, weight gain, blurred vision, constipation, lack of sex drive and a dry mouth
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AO2 Evaluation - Atypical drugs have been found to be tolerable to patients with schizophrenia
National Institute of Mental Health - 3/4 of all patients stopped taking their medications, however they stayed on clozapine for 11 months, compared to 3 months seroquel
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AO2 - Evaluation
Davis et al - Relapse occured in 55% of patients whose drugs were replaced with placebo, and 19% of those who remained on the drug
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Other cards in this set
Card 2
Front
Atypicals such as Clozapine, work differently in that they attach to specific DZ dopamine receptors. Good for positive systems, however comparative affects on negative are marginal (Leucht et al)
Back
Atypical - Newer and less widely used - Have fewer side effects and act in different ways to antipsychotic drugs
Card 3
Front
Drowsiness, weight gain, blurred vision, constipation, lack of sex drive and a dry mouth
Back
Card 4
Front
National Institute of Mental Health - 3/4 of all patients stopped taking their medications, however they stayed on clozapine for 11 months, compared to 3 months seroquel
Back
Card 5
Front
Davis et al - Relapse occured in 55% of patients whose drugs were replaced with placebo, and 19% of those who remained on the drug
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