Schizophrenia may be hereditary, as the risk of developing the disorder is higher in individuals whose relatives suffer from it
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WHich genes are thought to causes schizophrenia?
no one gene is thought to causes schizophrenia but a combination of different ones may make an individual more susceptible to developing the disorder.
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What did Gotttesman's (1991) family study test?
It got schizophrenia sufferers and identified how often their biological family suffered similar disorders compared with their non-biological family
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What did Gotttesman's (1991) family study find?
Gottesman found that the closer the degree of genetic relatedness the greater the risk of schizophrenia
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What were the biological family concordance rates for Gottesman's family study?
Children with 2 schizophrenic parents: 46%, Children with 1 schizophrenic parents: 13% siblings with Schizophrenia: 9%
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Who pooled concordance rates of MZ ans DZ twins in prior to 2001?
Joseph (2004)
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What level of concordance rates did twin studies show?
Joseph found that MZ had twins 40.4 and DZ twins had 7.4%
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What have later 'blind' diagnosis shown about twin studies?
blind diagnosis have identified lower concordance rates for MZ twins than in earlier studies, but overall support for twin studies still remains high
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Why are adoption studies used?
to make a distinction between genetic and envinronmental factors of schizophrenina
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What did Teinari (2000) find to support the biological explination of schiozophrenina?
11 (6.7%) if finnish adoptees whose mothers were diagnosed with schizophrenia were similarly diagnosed compared with only 4 (2%) of the 197 control group pps
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What is the premise of the dopamine hypothosis?
the dopamine hypothosis claims that an exsess of the neurotransmitter, dopamine in certain areas of the brain can cause schizophrenia
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How does dopaine effect the postive symptoms of schizophrenia?
an abundence of messages firing from neurons that transmit dopamine can cause hallucinations and dellusions
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how might schizophrenics be predisposed to high levels of dopamine?
It is thought that schizophrenics have high levels of the receptor D2 on reciving nerons
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What effect does an abundence of D2 receptors have on on the brain?
it results on more dopamine bidning and thus more firing
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How does amphetimine support the dopamine hypothosis?
as amphetamine is a dopamine agonist it can cause postive symptoms of schizophrenia in "normal" people
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Other cards in this set
Card 2
Front
WHich genes are thought to causes schizophrenia?
Back
no one gene is thought to causes schizophrenia but a combination of different ones may make an individual more susceptible to developing the disorder.
Card 3
Front
What did Gotttesman's (1991) family study test?
Back
Card 4
Front
What did Gotttesman's (1991) family study find?
Back
Card 5
Front
What were the biological family concordance rates for Gottesman's family study?
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