Biological explanations of Schizophrenia: Biochemicals

1. Barlow & Durand found that ______________ is effective in reducing SZ symptoms in about 60%, mostly impacting positive symptoms. (13)
4. Excessive amounts of dopamine in the D2 receptors ________ the normal process of regulating attention. (8)
5. The Dopamine hypothesis suggests that the D2 dopamine pathway controls _________ so when it is over activated it can lead to symptoms of schizophrenia. (9)
6. __________ disease shows low levels of dopamine and similar SZ negative symptoms. If taking too much L-dopa they can show positive symptoms of SZ. (10)
9. Timmons et al reported high doses of ___________ can result in acute psychosis resembling SZ in clinically normal people. (11)

2. Amphetamines lead to an ________ in dopamine levels and large quantities can lead to delusions and hallucinations. (8)
3. Lindstroem et al _____________ labelled L-dopa and administered it to 10 SZ and 10 non SZ, finding that the L-dopa was taken up quicker with SZ patients. (13)
7. Falkai et al found that _________ showed SZ sufferers have larger dopamine receptors, increase DA in the brain structures and receptor density. (9)
8. Research has found that chemical ___________ in rats of dopamine agonist lead to similar behaviour of positive symptoms in SZ. (11)

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