Biological Approach to OCD

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What did Billet et al find for Identical twins?
if one twin had OCD, the other twin has a 68% chance of developing it
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What did billet et al find for Non identical twins?
If one twin had OCD, the other twin has a 31% chance of developing it
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What did Paul et al find?
People with immediate relatives who had OCD had 10% of developing it, but people whose relatives did not have it had 2% chance of developing it.
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What did Insel find?
People who had OCD and took SSRIs had a 50-60% improvement on their symptoms
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What did Zohar et al find?
60% of his patients with OCD had reduced symptoms after taking SSRIs
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What did Max et al find?
People with head injuries had damage to basal ganglia often had OCD
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What have other researchers found about the basal ganglia?
people with diseases which involve the basal ganglia often have OCD (ie parkinson's or Huntington's)
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Strengths to the Biological approach to OCD?
Scientific- biological evidence/ Ethical- does not blame person for their illness/ Twin studies- show effect of developing OCD
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Weaknesses to the Biological approach to OCD?`
other factors not taken into account, ie environment, family, childhood experiences etc/ Ethics- SSRIs may be addictive.
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Treatment for OCD
SSRIs increase Serotonin so reuptake in the synaptic cleft (gap between 2 neurons), there is more serotonin available to next neuron
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Advantages for Treatment?
Thoren et al found SSRIs reduce obsessive thoughts, other antidepressants don't increase serotonin aren't effective.
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Disadvantages for Treatment?
Upto 50% patients do not have improvements to symptoms, relapses, can take a few weeks to work, side effects.
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Card 2

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What did billet et al find for Non identical twins?

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If one twin had OCD, the other twin has a 31% chance of developing it

Card 3

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What did Paul et al find?

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Card 4

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What did Insel find?

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Card 5

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What did Zohar et al find?

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