Biological approach: Neurotransmitter

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Dopamine Hypothesis
Either; too much dopamine or the receptors are too sensitive
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Support Dopamine Hypothesis
L-Dopa = Phenothiazine - Speeds up dopamine, LSD & Amphetamines = Give Sz symptoms - They increase the amount of dopamine
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Ranrup & Munkvad
Gave rats amphetamines (activate dopamine production) - creating Sz-like symptoms - Gave them neuroleptic drugs (inhibit release of dopamine) - Reversed the effects
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Iversen
Reported that post mortems on people who were Sz had excess dopamine in the limbic system - Suggesting dopamine is involved in the disorder
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Kesler et al
Used MRI and PET scans to compare Sz and non-Sz patients - They found differences in dopamine levels - Suggesting dopamine is important in the onset of Sz
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Card 2

Front

L-Dopa = Phenothiazine - Speeds up dopamine, LSD & Amphetamines = Give Sz symptoms - They increase the amount of dopamine

Back

Support Dopamine Hypothesis

Card 3

Front

Gave rats amphetamines (activate dopamine production) - creating Sz-like symptoms - Gave them neuroleptic drugs (inhibit release of dopamine) - Reversed the effects

Back

Preview of the back of card 3

Card 4

Front

Reported that post mortems on people who were Sz had excess dopamine in the limbic system - Suggesting dopamine is involved in the disorder

Back

Preview of the back of card 4

Card 5

Front

Used MRI and PET scans to compare Sz and non-Sz patients - They found differences in dopamine levels - Suggesting dopamine is important in the onset of Sz

Back

Preview of the back of card 5

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