Atherosclerosis

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What is atherosclerosis?
a disease where the wall of arteries becomes furred up with fatty deposits
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hat are the fatty deposits called?
plaques or atheromas
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What is the first step of atherosclerosis?
The endothelial layer on the inside of an artery is damaged
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What occurs of the artery wall?
Inflammation
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What moves into the artery wall?
White blood cells
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What begins to accumulate at the site of damage?
Cholesterol
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What forms?
Atheroma
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What narrows?
Lumen
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What increases?
Pressure
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What speeds up atheroma?
Hypertension
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Clot
Formation
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What is activated by substances released by the damaged artery wall?
Platelets
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What do platelets become?
sticky
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What do they form?
A platelet plug
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On the surface of what?
the atheroma
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Platelet releases chemicals which activate?
Thromboplastin
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What does Thromboplastin initiate?
The clotting cascade
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What is the first reaction in the clotting cascade?
Prothrombin to thrombin
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What does thrombin catalyse?
Insoluble fibrinogen to soluble fibrin
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what occurs in the brain?
A stroke
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In the coronary arteries?
CHD
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Other cards in this set

Card 2

Front

hat are the fatty deposits called?

Back

plaques or atheromas

Card 3

Front

What is the first step of atherosclerosis?

Back

Preview of the front of card 3

Card 4

Front

What occurs of the artery wall?

Back

Preview of the front of card 4

Card 5

Front

What moves into the artery wall?

Back

Preview of the front of card 5
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