Atherosclerosis 0.0 / 5 ? BiologyHealth, illness and diseaseA2/A-levelEdexcel Created by: francesca_321Created on: 21-02-16 16:35 What is atherosclerosis? a disease where the wall of arteries becomes furred up with fatty deposits 1 of 21 hat are the fatty deposits called? plaques or atheromas 2 of 21 What is the first step of atherosclerosis? The endothelial layer on the inside of an artery is damaged 3 of 21 What occurs of the artery wall? Inflammation 4 of 21 What moves into the artery wall? White blood cells 5 of 21 What begins to accumulate at the site of damage? Cholesterol 6 of 21 What forms? Atheroma 7 of 21 What narrows? Lumen 8 of 21 What increases? Pressure 9 of 21 What speeds up atheroma? Hypertension 10 of 21 Clot Formation 11 of 21 What is activated by substances released by the damaged artery wall? Platelets 12 of 21 What do platelets become? sticky 13 of 21 What do they form? A platelet plug 14 of 21 On the surface of what? the atheroma 15 of 21 Platelet releases chemicals which activate? Thromboplastin 16 of 21 What does Thromboplastin initiate? The clotting cascade 17 of 21 What is the first reaction in the clotting cascade? Prothrombin to thrombin 18 of 21 What does thrombin catalyse? Insoluble fibrinogen to soluble fibrin 19 of 21 what occurs in the brain? A stroke 20 of 21 In the coronary arteries? CHD 21 of 21
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