Antidepressant Medication and CBT

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What is the NICE guideline for antidepressant use on LI patients?
Do not use routinely because risk-benefit ratio is poor. Only consider for people with history of moderate/ severe depression, symptoms persistent for 2 years, symptoms persist after other interventions.
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What is the NICE guideline for antidepressant use on HI patients?
Discuss drug options with patient, covering adverse effects and perceptions of efficiency. Should normally use SSRIs.
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What do SSRIs do?
Prevent the reuptake of serotonin in the synapse, resulting in increased serotonin transmission.
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What is wrong with the serotonin hypothesis?
Little evidence of a strong correlation between serotonin levels and depressed mood, SSRIs are not superior to older medication that does not target serotonin.
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What are the possible adverse consequences of SSRIs (4)?
Sleep disturbance, weight gain, sexual dysfunction, irregular cardiac function.
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What are the implications for EBM?
Findings of the same research can be legitimately interpreted in different ways by different readers, or illegitimately manipulated by interested parties.
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What is the cognitive theory of depression?
Our emotions are shaped by how we construe a situation, not the situation itself.
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How is depression vulnerability caused and activated?
Its a result of dysfunctional beliefs established in early experience, which become activated by events carry a specific meaning for the individual.
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What may the negative triad of beliefs be sustained by?
Negatively biased information processing.
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What is cognitive therapy?
Helps clients identify and reevaluate distorted cognitions using behavioural and cognitive techniques to correct thinking errors. It is a structured approach focusing on relapse prevention.
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What is CBT for depression?
Works by changing the content of negative thinking. The degree to which negative thinking is changed should predict the extent of symptom improvement for the client.
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What is the NICE guideline for antidepressant use on HI patients?

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Discuss drug options with patient, covering adverse effects and perceptions of efficiency. Should normally use SSRIs.

Card 3

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What do SSRIs do?

Back

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Card 4

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What is wrong with the serotonin hypothesis?

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Card 5

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What are the possible adverse consequences of SSRIs (4)?

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