Aggression- Genetics

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1. Study of MAOA in humans, found after abuse and maltreatment, those with high activity MAOA gene were less likely to be aggressive than those with low activity MAOA gene

  • Alcock
  • Capsi et al
  • Mattson
  • Bruner
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2. Studied MAOA gene in mice. Mice lacking the MAOA gene had serious anger management problems

  • Capsi et al
  • Nannini
  • Mattson
  • Bruner

3. Methods of studying genetics: Selectively breeding animals to see if aggression is a hereditary trait

  • Heritability
  • Genetic Manipulation
  • Case Study

4. High activity MAOA ensures:

  • excess neurotransmitters are reduced meaning reduced aggression
  • increases neurotransmitters to reduce aggression
  • excess neurotransmitters are reduced meaning increased aggression

5. Case study of dutch family. Found extremely violent members had low levels of MAOA

  • Mattson
  • Bruner
  • Capsi
  • Shackleford

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