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6. Which of these is true of paragangliomas?

  • RET gene is implicated
  • Derived from cells normally acting as chemoreceptors
  • Derived from cells of the medulla
  • Derived from chromaffin cells

7. Which of these is a tumour of the adrenal cortex?

  • Ganglioneuroma
  • Pheochromocytoma
  • Adenoma
  • Neuroblastoma

8. Adrenaline causes which of the following?

  • Vasoconstriction in the liver
  • Vasodilation in the liver
  • Systemic vasodilation
  • Vasoconstriction in the muscles

9. Which of these statements is true?

  • ACTH is hypersecreted in CAH
  • 17-hydroxyprogesterone is normally converted to aldosterone
  • CAH is autosomal dominant

10. Which of these actions does cortisol cause?

  • Increased production of tumour necrosis factor
  • Increased gluconeogenesis
  • Protein synthesis
  • Increases glucose transporters

11. Tertiary adrenal insufficiency is caused by what?

  • Hypothalamic pathology
  • Pituitary pathology
  • Adrenal pathology

12. Which of these is a presentation of Addison's disease?

  • Weight gain
  • Striae
  • Hypotension
  • Hypertension

13. Which of these is indicative of primary hyperaldosteronism?

  • Hypotension
  • Suppressed renin
  • Increased renin
  • Hyperkalaemia

14. Which of these is a cause of pseudo-cushing's?

  • Amyloidosis
  • Prolonged alcohol excess
  • Tuberculosis
  • Long term steroid use

15. Aldosterone enhances the reabsorption of hydrogen ions in the kidney

  • False
  • True

16. Which of these is true of type 1 neurofibromatosis?

  • Autosomal recessive
  • Causes microcephaly
  • Causes paragangliomas in 75%
  • Causes benign pheochromocytomas in 75%

17. Which of these is not a cause of primary hyperaldosteronism?

  • Cortical carcinoma
  • Congenital adrenal hyperplasia
  • Bilateral adrenal hyperplasia
  • Aldosterone producing adenoma

18. Which of these is not indicative of Cushing's syndrome?

  • Spinal tenderness
  • Weight Loss
  • Osteoporosis
  • Hypertension

19. Conn's syndrome is what?

  • A form of secondary hyperaldosteronism
  • A form of primary hyperaldosteronism
  • A form of primary hypercortisolism
  • A form of secondary hypercortisolism

20. Von-Hippel-Lindau syndrome causes what?

  • Gliomas of CNS
  • Pheochromocytomas of the mediastinum
  • Neurofibromas
  • Thyroid cancer