Active sites 0.0 / 5 ? Applied ScienceEnzymes: active sitesA2/A-levelAQA Created by: OliveCreated on: 15-07-21 14:09 Secondary structure Means that polypeptide chains form orderly shapes 1 of 15 Hydrogen bonds The secondary structures are held in shape by hydrogen bonds between the -NH of one peptide link and the -C=O of another amino acid 2 of 15 The most common shapes of secondary structure are: Coiled: Ą -helix and ß -pleated sheet 3 of 15 Tertiary structure Is the secondary structure folds into three dimensional shapes to make it 4 of 15 Active site This is the part of the enzyme where the substrate binds to 5 of 15 What happens when a substrate enters the active site: When a substrate enters the active site of the enzyme, the enzyme-substrate complex is formed 6 of 15 What happens at the active site? This is where the catalytic action happens 7 of 15 What happens when an enzyme catalyses a reaction? The reaction takes place on the active site of an enzyme 8 of 15 What does the active site consist of? Consists of a small number of amino acids which form a specific shape due to the secondary and tertiary structure 9 of 15 Biochemical reaction E.G.: The enzyme amalase specifically breaks down starch but does not break down protein 10 of 15 In a biochemical reaction Substrates are converted into products 11 of 15 The substrate has a complimentary shape So only specific substrates will bind to a particular enzymes site 12 of 15 After the reaction: The product is released and the active site is able to catalyse further reactions 13 of 15 If the temperature gets too high: (e.g. 40˚c) The hydrogen bonds will break 14 of 15 If the hydrogen bonds break: The enzyme changes its shape, so the active site loses its shape leaving the enzyme denatured and unable to catalyse more reactions 15 of 15
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