4.2.3 SYNTHESIS

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Why are chiral drugs used?
minimise side effects/ economically reasons/ reduce risk to companies from litigation/ required production of single optical isomer
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Outline the formation if chiral compounds
naturally only one isomer made/ synthesised in lab 2 are made/ pharmaceuticals often require only one as one is active
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What are the cons of reducing pharmaceuticals that contain a mix of isomers?
unwanted side effects/ expensive to separate/reduces effectiveness as larger dose needed
3 of 5
explain the modern synthesis of single isomer pharmaceuticals
using enzymes or bacteria (stereoselectivity)/ chemical chiral synthesis or chiral catalysts/ using natural chiral molecules
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Card 2

Front

Outline the formation if chiral compounds

Back

naturally only one isomer made/ synthesised in lab 2 are made/ pharmaceuticals often require only one as one is active

Card 3

Front

What are the cons of reducing pharmaceuticals that contain a mix of isomers?

Back

Preview of the front of card 3

Card 4

Front

explain the modern synthesis of single isomer pharmaceuticals

Back

Preview of the front of card 4

Card 5

Front

...

Back

Preview of the front of card 5

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