4.2.3 SYNTHESIS

Why are chiral drugs used?

minimise side effects/ economically reasons/ reduce risk to companies from litigation/ required production of single optical isomer

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Outline the formation if chiral compounds

naturally only one isomer made/ synthesised in lab 2 are made/ pharmaceuticals often require only one as one is active

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What are the cons of reducing pharmaceuticals that contain a mix of isomers?

unwanted side effects/ expensive to separate/reduces effectiveness as larger dose needed

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explain the modern synthesis of single isomer pharmaceuticals

using enzymes or bacteria (stereoselectivity)/ chemical chiral synthesis or chiral catalysts/ using natural chiral molecules

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Other cards in this set

Outline the formation if chiral compounds

naturally only one isomer made/ synthesised in lab 2 are made/ pharmaceuticals often require only one as one is active

What are the cons of reducing pharmaceuticals that contain a mix of isomers?

explain the modern synthesis of single isomer pharmaceuticals

...

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