hypothalamus which produced TRH stimulates anterior pituitary gland to produce TSH which stimulates thyroid gland to make T4/T3. Thyroid gland sends a signal to the hypothalamus to decrease the section of TRH, also thyroid sends a signal to anterior pitui
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By what hormones is the pituitary gland stimulated and what does it produce.
what hormones are produced by the posterior pituitary gland
anti-diuretic hormone (vasopressin)
oxytocin
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give examples of hormones secreted by non pituitary systems
adrenaline, aldosterone, insulin and glucagon, parathyroid hormone
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what are the investigations for endocrine disorders
• Blood analysis of pituitary hormones and organ hormones
• Imaging of brain and endocrine organs (CT, MRI)
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how would hormone insufficiency and hormone excess be managed
insufficiency= replacement and monitor in terms of homeostasis
excess= suppression and monitor
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what does ADH do and how
regulates plasma osmolality by affecting renal tubular water resorption
prevents diuresis if plasma osmolality- thereby conserving water in states of dehydration
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what is diabetes insipidus
Lack of ADH produced in hypothalamus or renal insensitivity to ADH
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what are the symptoms of DI
polyuria (weeing a lot), polydipsia (drinking a lot) and dehydration if inadequate fluid intake. Can be 10-15 litres urine per day.
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How would DI be managed
• Synthetic ADH (desmopressin, DDAVP) if lack of ADH
• Intranasal, sublingual, injectable and oral formulations available
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