Synaptic Transmission

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Explain the principles of synaptic transmission

Chemical Synapses

In the synapse, the arrival of an action potential causes a change in membrane permeability for Ca2+ . As a result these calcium ions flow into the synaptic knob. 

The consequence of this is exocytosis of a transmitter substance in vesicles. 

This neurotransmitter then diffuses across the synaptic cleft and attaches to receptors in


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