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Summation at synapses finely tunes the nervous response


If a stimulus is weak, only a small amount of neurotransmitter will be released from a neurone into the synaptic cleft. This might not be enough to excite the postsynaptic membrane to the threshold level and stimulate an action potential. Summation is where the effect of neurotransmitter released from many neurones (or one neurone that is stimulated a lot in a short period of time) is added together. There are two types of summation:


  1. Temporal Summation


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