Sliding Filament Model

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  • Impulses reach the neuromuscular junction and cause synaptic vesicles to bind with the pre-synaptic membrane and release acetylcholine
  • Acetylcholine binds with receptors on the sarcolemme and with depolarises the sarcolemma
  • If a threshold level is reached, the T-system is also depolarised
  • Calcium ions are released from the T-system and the sarcoplasmic reticulum 
  • These ions bind to the troponin, changing it shape 
  • The troponin, which secures the…


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