The closer the genetic relatedness the higher the likely concordance for schizophrenia.
The risk of schizophrenia for the general population is about 1%
Gottesman and Shields
- Parent 5.6
- Siblings 10.1
- Siblings with one schizophrenic parent 12.9
- Child with two schizophrenic parents 46.3
- Grandchildren 3.7
Schizophrenia does tend to run in families BUT nature or nurture?
- Monozygotic twins: 100% genes: 46% concordance
If schizophrenia were just a…