Protein structure, binding and conformational change.

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  • Created by: Vincemma7
  • Created on: 31-10-18 20:04

Amino acid sequence determines protein structure.

Proteins are polymers of amino acid monomers. Amino acids link by peptide bonds to form polypeptides. The primary structure is the sequence in which the amino acids are synthesised into the polypeptide. Hydrogen bonding along the backbone of the protein strand results in regions of secondary structure — alpha helices, parallel or anti-parallel beta sheets, or turns. 

The polypeptide folds further into a tertiary structure.

This conformation (shape) is caused by interactions between the groups.

The 3D structure is maintained by:

  • Hydrogen bonds 

  • Ionic bonds

  • Disulphide bonds 

  • Hydrophobic interactions between R groups.

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