Molecular Biology; 3

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DNA REPLICATION

PROKARIOTIC, EUKARIOTIC CELLS

Prokaryotes

Nucleoid:

- Single, circular chromosomal DNA (prokaryotic chromosome).

- Structural and functional genes to generate a copy of the prokariot organism.

- Transmission by binary fission (cell division)

Plasmid:

- Separate smaller circular DNA structures

- Genes that may benefit survival of the organism (e.g. antibiotic resistance)

- Transmission by horizontal gene transfer (conjugation).

DNA is circular and has a single replicon (in bacteria)

DNA replication steps;

1) DNA unwinds- repeating 9 neuclotides (9mers) is where initial binding

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