Maguire

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AIMS: 

  • to show that the hippocampus has plasticity
  • show that the hippocampus volume changes depending on level of navigational skill

METHOD:

  • Quasi experiment
  • IV - taxi driver/non taxi driver
  • DV - hippocamus volume

PARTICIPANTS:

  • Taxi drivers: 16 males, licenced for more than 18 months, london, aged 32-64, all right handed, clincally normal and had passed 'the knowledge'
  • non taxi drivers: 50, all male, right handed, 32-64, routine MRI scans taken from database (not in person)

PROCEDURE:

  • All 16 taxi drivers were given an MRI scan
  • comparissons were made to their matches in other condition (some had 3/4)
  • Measured VBM (voxel based morphometry) - 3D measurement of the volume of grey matter
  • Pixel counting - 2D measurement,  26 slices of scan - density of grey matter around hippocampus (1 before, 6 on posterior HC, 12 on HC body, 6 on anterior HC, 1 after)
  • VALID BECAUSE DONE BY 1 EXPERIENCED SCAN OPERATOR
  • operator was condition blind, 

RESULTS:

  • Taxi drivers had increase in volume of grey matter in left/right posterior hippocampus
  • Taxi drivers had decrease in volume of…

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