Krebs Cycle and the Electron Transport Chain

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Krebs Cycle and the Electron Transport Chain

1. Describe how the Krebs cycle produces carbon dioxide, ATP, reduced NAD and reduced FAD

The Link Reaction

  • If oxygen is available, pyruvate created from glycolysis travels to the mitochondria where it is oxidised to form carbon dioxide and water.
  • Pyruvate is decarboxylated - carbon dioxide is released as a waste product.
  • Pyruvate is dehydrogenated - two hydrogens are removed and taken up by the coenzyme NAD.
  • A 2C molecule results and combines with coenzyme A to form acetyl coenzyme A (Acetyl CoA). 
  • The 2C acetyl groups are carried to the Krebs cycle by coenzyme A.

The Krebs Cycle

  • Occurs in the matrix of the mitochondria (so does the link reaction)
  • Purpose is to supply a continuous flow of hydrogen (and electrons) to the electron transport chain.
  • Each 2C acetyl coenzyme A combines with a 4C compound to create a 6C compound.
  • A circule of reactions recreate the original 4C compound. 


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