Enzymes week one - Synch class

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Hydrolases 

  • Hydrolases break down other molecules.
  • They are both in the digestive system.
  • Both use water to break down molecules.
  • Both produced by pancreas.
  • If deficient in either causes illness. 
  • Essential for breakdown.
  • Enzyme activity is based on pH and place where it is found. 
  • Protaese and amylase are both used in the medication.
Isomerase
  • Isomerase is an enzyme that catalyses the conversion of a specified compound to an isomer.
  • They're involved in structural rearrangements of molecules.  
  • Isomerase catalyse changes that happen within one molecule
  • ligases catalyses the joining or ligation of two large molecules by forming a new chemical bond usually with accompanying hydrolysis of a pendant small chemical group
  • Isomerases catalyse reactions across many biological processes, such as in glycolysis and carbohydrate metabolism.
  • Effects: TPI deficiency can lead to disorder such as hemolytic anemia, neurological problems, infection and muscles weakness which can cause abnormalities such as heart and breathing problems.  
Fumarase and Carboxylases (hydro-lyase)
  • Catalyses the breakdown of larger molecules into smaller molecules with addition of water.
  • Class of enzyme performs as biochemical catalysts that use water to break a chemical bond, which typically results in dividing a larger molecule to smaller molecules (catalyzes hydrolysis reaction)
  • Hydrolases - split molecules by addition of water
  • Lyases - split molecules without addition of water
  • Function of most hydrolases is digestive - to break down nutrients into smaller units for digestion. 
  • Facilitate intramolecular rearrangements in which bonds are broken and formed.
  • Classified as alpha…

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