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Depression - drugs

1960's - introduced 2 groups of drugs:

  • Monoamine-oxidase inhibitors ( MAOIS )
  • Tricyclic antidepressants

Monoamine theory of depression: Depression related to low levels of serotonin and noradrenaline - drugs raise these levels.

But both groups serious side effects:

MAOIS = interact badly with some food groups and medication

Tricyclics…

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