Carboxylic acids derivitives reactions UNIT 4 edexcel A2

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Acyl Chlorides/Acid Chlorides

Acyl Chloride + alcohol= Ester and water

Conditions room temperature ( no acid cataylst is needed as the acyl choride is far more reactive as chloride is a far better leaving group as it is so electron negative.

Acyl chloride + conc NH3 = amide and HCl

Conditions this is done in a glass tube which is sealed and heated( and yes very dangerous)

Acyl chloride + water = carboxylic acid

Conditions room temperature

Acyl Chloride + Amine = N-subsituted Amide +HCl

Conditions room temperature

Esters can be turned back into the acid and…

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