Biological Explanations for Schizophrenia.

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  • Created by: Emily
  • Created on: 08-05-12 19:01

Genetics.

Schizophrenia can run in families.

Family Studies:

A first degree relative shares 50% of genes. (Second degree shares 25%.)

Kendler et al showed first degree relatives are 18 times more at risk than the general population.

Evaluation:

Family studies are often inconclusive because they are conducted retrospectively.

They compare those already diagnosed. A longitudinal study can provide more reliable data.

Twin Studies:

To separate genes from environment, researchers found M.Z twins raised apart, where one twin has schizophrenia.

Gottesman and Sheilds used the Maudsley twin register and found 58% concordance.

Offspring of a non-affected twin should also be at risk, Fischer found that

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