Anaemia and Thalassemia

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  • Created by: claudsia
  • Created on: 05-01-22 16:45

Anaemia and Thalassemia

Clinical Symptoms of Anaemia

-          g/dL = grams of haemoglobin p decilitre of Plasma

Common Symptoms - 

  • Unexplained fatigue and loss of energy
  • Characteristic pallor, coldness, possible yellowing of skin + eyes
  • palpitations and shortness of breath (dyspnea) esp during excercise
  • dizziness + faitness; headache

90% of anemic ppl in developing countries. It is a huge issue in countries such as India were 1/5 of maternal deahts is caused by anaemia.

Symptoms + signs of anaemia on:

Cardiovascular System:

- Angina 

- Intermittent claudification - spasmic clampin in calf muscle

CNS:

- Headache - can lead to accidents in older ppl

- fainting, tinnitus, decr ability to concentrate etc. more sever in olde rpatient for symptoms

  • Mild and moderate anaemia --> 8 -12 g/dL
  • Severe anaemia --> <8 g/dL

Most sever form is orthotnaeia – v ill person can’t lie flat in bed bc they get so breathless when they do – sign of the heart failing.

Classification of Anaemias

System 1: Physiology

- blood loss like undetected haemorrhaging - anaemia consequence

System 2: Morphology

- Normal cells is Normocytic

MCV = Mean Corposcular Volume - i.e. red cell volume

Fl is 10 to -15 ( a v tiny scale). In general the scale of size is 80-100fl. 

  • Under 80fl the red blood cells are said to be microcytic…

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