A2 Biology Genomes notes part 1

Sequecing  the genome of an organism 

• genomes are mapped to find out which part of the genome they are form this can be done using microsatellites 
• samples of the genome are mechanically broken up into smaller section up to 100 000 base pairs
• these sections are placed in separate bacterial artificial chromosomes and then transported to e coil
• cells are grown in culture and many clones of the section are produced 
• cells are then known as clone libraries

comparisons

• identification of the genes that codes for proteins can be compared 
• mutant alleles that cause disease can…