Around 125cm3 of fluid is filtered from the blood per minute and enters the nephron tubules. After selective reabsorption there is around 45cm3 left.
The role of the Loop Of Henle is to create a LOW, NEGATIVE water potential in the TISSUE of the medulla. This ensures even more water can be reabsorbed from the fluid in the collecting duct.
Loop Of Henle:
- Consists of a DESCENDING LIMB that descends into the medulla and an ASCENDING limb that ascends back out to the cortex.
- Arrangement of the loop of Henle allows salts (SODIUM and CHLORIDE ions) to be transferred from the ASCENDING limb to the DESCENDING limb.
- The overall effect is to INCREASE the concentration of SALTS in the tubule fluid and they DIFFUSE out from the thin-walled ASCENDING limb into the MEDULLA TISSUE, giving the tissue fluid in the medulla a very LOW/NEGATIVE water potential.
How is this achieved?
Water potential in fluid in tubule becomes lower, because:
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