· In prophase the mitotic spindle forms.
· In prometaphase the chromosomes attach to the mitotic spindle at the centromere
· In metaphase, the condensed chromosomes align in a plane across the equator of the mitotic spindle.
· Anaphase follows as the separated chromatids move abruptly toward opposite spindle poles.
· Finally, in telophase a new nuclear envelope forms around each set of unraveling chromatids.
· The mitotic spindle is composed of microtubules, each of which is a tubular assembly of molecules of the protein tubulin.
· Microtubules can grow or shrink by the addition or removal of tubulin molecules. This change in length propels attached chromatids to the spindle poles, where they unravel to form new nuclei.
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