treatment since 1900

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magic bullets (card 1)

koch discovered different chemical dyes stained specific microbes

behring dicovered the body manufactures antitoxins that only attack the microbe causing a disease

ehrich and his team did research for a 'magic bullet'- chemical compound that would attack and kill the microbe causing a specific disease

helped by german government funding, tested many compounds of salvarsan to find one to cure syphilis


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magic bullets (card 2)

in 1909, dr hata joined the team

realised they had rejected a compound that worked- 606

in 1932, domagk developed the second magic bullet-prontosil, which cured some types of blood poisoning

domagk's work was checked, and the key ingredient in prontosil was sulphonamide- also cured pneumonia, scarlet fever and meningitis

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penicillin(card 1)

in 1928, fleming noticed that bacteria in a petri dish was being killed by a penicillium mould

he tested it for other bacteria

discovered that the mould produced an excellent antibiotic- penicillin

in 1929, fleming published his findings, but had no funding

years later, florey and chain, and their team contined fleming's work


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penicillin(card 2)

proved to be effective on mice

tested it on humans. penicillin killed bacteria, was a 'miracle drug'

had to be grown in large quantites, british factories and drug companies worked hard to produce other drugs for the war

asked US companies for help they said no

when US entered the war & antibiotics was needed, the US government funded

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growth of the pharmaceutical industry

chemical cures and substances that cure bacteria infections led to rapid growth in the pharmaceutical industry

were originally injected, but technology developed in the late 19th century was now used to mass produce pills

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blood transfusions

in 1901, landsteiner discovered there was four blood groups

a donor and the patient had to have the same blood group for the transfusion to work

blood clotted quickly so the patient and the donor had to be together

during WW1 they had sodium citrate to stop the blood from clotting, allowing it to be stored for longer

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