Where a neurone meets a skeletal muscle fibre
There are many junctions along the muscle in order for muscles to contract simutanously and fast movement
All muscle fibres supplied by a single motor neurone act together as a single functional unit (motor unit). This arrangment gives control over the force that the muscle exerts. If only slight force needed, only a few units are stimulated
When nerve impulse is recieved at neurotransmitter junction, the synaptic vesicles fuse with the pre-synaptic membrane and release their acetylcholine
Acetylcholine diffuses to post-synaptic membrane, altering its permablilty to sodium ions, which enter rapidly, depolarising membrane
Acetylcholine is broken down by acetylcholinesterase to ensure muscle isn't over stimulated
Resulting choline and ethanoic acid diffuse back into neurone, where its recombined to form acetylcholine using energy provided by mitochondria
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