Respiratory substrates

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Respiratory substrates

...substances broken down in respiration to produce ATP (Hexose sugars, lipids, proteins (Amino acids)


  • 1) Lipids must be broken down into gylcerol and fatty acids
  • 2)a) Glycerol is then phosphated before entering gylcolysis as triose phosphate
  • b) Fatty acids are broken down in the beta oxidation pathway and combine with acetylcoenzyme A and enter the Kreb's cycle


  • 1) Proteins are broken up into amino acids
  • 2) Amino acids undergo deamination
  • 3a) Deaminated amino acids with 3 carbons enter the link reaction as Pyruvate
  •   b) Deaminated animo acids with 4 carbons enter the Kreb's cycle as oxaloacetate
  •   c)Deaminated amino acids with 5 carbons enter the Kreb's cycle as alpha Ketogluterate
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Respiratory Quotients

...a measure of the raio of carbon dioxide evolved to oxygen consumed

RQ = CO2 evolved/O2 consumed

This value also indicated which respiatoryr substrate is being used in respiration

  • Carbohydrates:- 1
  • Lipids: 0.7
  • Proteins: 0.9 - this can also indicate that the respiratory substrates are a combination of carbohydrates and lipids

A value above one indicates that anaerobic respiration may be occuring

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