Segerstrom and Miller (2004)
Meta-analysis of 293 studies over 30 years
Three Conclusions
- Short-term, acute stressors can boost the immune system, prompting to ready itself for infections or other challenges to the integrity of the body.
- Long-term, chronic stressors led to suppression of the immune system - the most chronic stressors were associated with the most global suppression of immunity.
- The longer the stress, the more the immune system shifted from potentially adapted changes to potentially detrimental changes.
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