The term gender dysphoria describes an individuals experience of feeling uncomfortable with the gender assigned to them at birth, which may result in sex change or gender reassignment.
The biological explanation:it is caused by unusual development in the brain before birth. There are small areas of the brain that are different in males and females. It is possible that hormones can cause parts of the brain to develop in a way that is not consistent with the genitalia and, usually, with the chromosomes. This means that the brain has not developed in a way that corresponds to the gender assigned to the child at birth.
Zhou et al studied one of the brain structures that is different in men and women and found that in six male-to-female transsexuals this followed a totally female pattern
Psychological explanation: Stoller - For boys who want to be girls, he suggests that there is an over-close relationship with the mother and a distant father. For girls who want to be boys, he suggests that that they have a depressed mother in the first few months of their life and a father who is either not present or does not support the mother but leaves the child to try to control the mother’s depression.
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