Electron Diffraction is the most accurate way to estimate the size and scattering of nuclei in a material, because electrons are leptons unlike alpha particles and thus do not interect via the strong nuclear force like alpha particles do.
It works because electrons show wave particle duality. A beam of high speed electrons (taking relativistic effects into account) has a wave length of approximately:
If this beam is directed at a material situated in front of a screen, then a pattern appears on the screen.
As with light diffraction patterns the first minimum occurs where:
Using these measurements the size and spacing fo the materials nuclei can be concluded.
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