Prophase
The chromosomes condense, getting shorter and fatter. Tiny bundles of protein called centrioles start moving to opposite ends of the cell, forming a network of protein fibres across the spindle. The nuclear envelope breaks down and chromosomes lie free in the cytoplasm.
Metaphase
The chromosomes (each with two chromatids) line up along the middle of the cell and become attached to the spindle by their centromere.
Anaphase
The centromeres divide, separating each pair of sister chromatids. The spindles contract, pulling chromatids to the opposite ends of the cell, centromere first.
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