Loop Of Henle

• Creates a salt concentration gradient in medulla
• Descends into the medulla, ascends into cortex
• Isotonic filtrate at the beginning
  • First part is short and fat
    • Impermeable to water and salts
• Hypertonic in the middle

Descending limb

•  
  • Thin descending limb is permeable to water
  • Not permeable to sodium and chloride ions

Ascending Limb

• Ion channels allow Sodium and Chloride out by fascilitated diffusion
• Thick part at the end has many mitochondria
  •  
    • Actively transports Sodium and Chlorine into Medulla
• Hypotonic at the end