The specific immune response involves the action of lymphocytes. The specific immune response involves several stages.
Activation of T-helper cells: T-helper cells use their CD4 receptors to attach to APCs (macrophages). This causes the T-helper cell to become activated, dividing producing active cells and T-memory cells.
Clonal selection: APC B cells have complementary receptor to activated T-helper cells and they bind. This releases cytokines and produces B memory cells and B effector cells. The B effector cells then differentiate into plasma cells which can produce antibodies.
T-killer cells: Infected cells displaying the antigen of the bacteria on their surface are then labelled by the antibodies produced, and T-killer cells have a complementary receptor and bind to them. This produces T-killer memory cells and active T-killer cells which then go on to bind to the infected cells and release chemicals which cause a pore to form in the cell, initiating cell lysis.
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