The homeostatic regulation of water is controlled by secretion of anti-diuretic hormone (ADH)
Osmoreceptor cells monitor the water content of the blood as it passes through the hypothalamus
Neurosecretory cells in the hypothalamus synthesise ADH and transport this along the axon of their nerves for storage in their synaptic end.
Osmoreceptor cells send action potential through the neurosecretory cells to the posterior pituitary if water content is low, secreting ADH and reabsorbing water into the bloodstream.
ADH is secreted and targets the collecting duct making it more permeable to water.
If the water content is too high no signal is sent for ADH secretion
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