Attention Deficit Hyperactivity Disorder (ADHD):- drugs such as Ritalin are used to treat it. ADHD affects dopamine levels in the brain. In a number of studies, a particular dopamine recpetor variant of DRD4, has been shown to be more frequent in individualssuffering from ADHD
Addicive and Risk Behaviours:- A number of studies have suggested that some variants of DRD4 receptor gene are implicated in increased likelihood of addictive behaviours like smoking. A study into the effects of administering L-dopa to one group of individuals and haloperidol (a drug that blocks dopamine recepors ) to another group showed not only a difference in general arousal, but also a significant difference in the risk-taking levels of the individuals
The interest in DRD4 and Dopmaine has stimulated research into other possible links between behviour and genetic constituion.
- OCD is though to result from a deficienc in the levels of the neurotransmitter seratonin. In 2007, a genome wide scan for DNA sequences related to OCD was carried out when the DNA from 1008 peopl from 219 families was analysed. Eight gentic markers were found that appear to be linked to OCD
Comments
No comments have yet been made