Also attempted to identify explanations for alzhiemers
One cause - a faulty protein (b-amyloid) is produced in brain and builds up between neurons forming plaques
Plaques prevent the neurons from communicating and damages the cerebal cortex, causing it to shrink
Berntson et al (2002) - plaque damage affects memory possibly because it causes AD
Snyder et al (2005) - maybe because b-amyloid interfers with a neurotransmitter involved in learning
Tangles could also be explanation for AD
Tau protein builds up on brain of people with AD - normally supports structure of neurons but in AD it forms tangles inside cell bodies of neurons when they die
Several genes associated with AD have been found
People with down's syndrome often have early onset AD - DS caused by extra copt of chromosone 21 so researchers tend to look for genes related to AD here
Genes found that affect production of b-amyloid explaining why some more likely to develop AD
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