- The liver is split into cylindrical lobules.
Blood is provided from two sources:
-Oxygenated blood: comes from the heart via the hepatic artery.
-Deoxygenated blood: comes from the digestive system via the hepatic portal vein.
Blood leaves the liver through the hepatic vein.
Bile duct carries bile from the liver to the gall bladder.
Alcohol detoxification: Competes for NAD, ethanol --> Ethanoate --> Acetyl CoA
Sinusoid: blood from the hepatic artery andportal vein joins = intra-lobular vessel
Liver cells: Remove and add molecules to blood in sinusoid, produce bile (bile canaliculi)
Kuppfer cells: specialised macrophages break down old red blood cells to form bilirubin.
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