Emphysema

caused by smoking.

• tar stimulates inflammatory response.
• alveoli loose elasticity.
• reduced tidal volume.
• e.c. may be destroyed.

symptoms are sevre breathing difficulties.

lung cancer 

• excess tissue in the lungs due to uncontrollable cell division.

risk factor is expose to mutagenic agents.

fibrosis

• particles stimulate inflammatory response.
• scar tissue.
• thickens alveolar walls, reduced elasticity, longer diffusion path.

symptoms are shortness of breath.