Development of Ovarian Follicle
-Ovarian follicle is a fluid filled structure that consists of the developing oocyte as well as other cells involved in the menstuation process
-Every month one of these primary follices containing a primary oocyte will devleop into a secondary follicle that contains a secondary oocyte
-During stimulation, secondary oocyte is released into the fallopian tubes while the remainder of cells develop into the corpus luteum.
-Other than the oocyte itself, there are two types of cells in the ovarian follicle:
(1) Theca Cell: Regulates Oogenesis and produces sex steroid hormones
(2) Granulosa Cell: FSH stimulates granulosa cells to convert androgens (coming from the thecal cells) to estradiol by aromatase during the follicular phase of the menstrual cycle.
General Process: LH acts on -> Theca cell = Cholesterol -> Androgen -> Travels to Granulosa cell; which with the aid of FSH; Androgen -> Oestrogen.