Cytokines Made by Macrophage

Learn the Cytokine Name and effects

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  • Created by: Chris mc
  • Created on: 09-04-11 19:24

Cytokine, effects, systemic effects

IL-1beta

Activate vascular endothelium

Activate Lymphocyte

Increased access effector cells

Fever

IL-6 Production 


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Cytokine, effects, systemic effects

TNF- Alpha

Activate vascular endothelium, increase vascular permeability

Increased IgG entry

Increased fluid drainage, and drainage to lymph nodes

Fever

Mobilization of metabolite

Shock

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Cytokine, local effects, systemic effects.

IL-6 

Lymphocyte activation

Increased antibody production

Fever

Induced acute phase protein production 

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Cytokine, local effect

IL-12

Activate Naturak Killers

Differentiation induced in CD4 T cells and TH1 cells

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Cytokine, local effects

CXCL8

Chemotactic factor, recruit neutrophils, basophils, T cells to infection site

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